Search on: AGOUTI-RELATED PROTEIN 
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Descriptor English:   Agouti-Related Protein 
Descriptor Spanish:   Proteína Relacionada con Agouti 
Descriptor Portuguese:   Proteína Relacionada com Agouti 
Synonyms English:   AGRP Protein
AGRT Protein
Agouti Related Protein  
Tree Number:   D12.644.276.074
D12.776.467.074
D23.529.074
Definition English:   A secreted protein of approximately 131 amino acids that is related to AGOUTI SIGNALING PROTEIN and is also an antagonist of MELANOCORTIN RECEPTOR activity. It is expressed primarily in the HYPOTHALAMUS and the ADRENAL GLAND. As a paracrine signaling molecule, AGRP is known to regulate food intake and body weight. Elevated AGRP has been associated with OBESITY. 
History Note English:   2008 (1997) 
Allowable Qualifiers English:  
AD administration & dosage AE adverse effects
AG agonists AN analysis
AI antagonists & inhibitors BI biosynthesis
BL blood CF cerebrospinal fluid
CS chemical synthesis CH chemistry
CL classification DF deficiency
DE drug effects EC economics
GE genetics HI history
IM immunology IP isolation & purification
ME metabolism PK pharmacokinetics
PD pharmacology PH physiology
PO poisoning RE radiation effects
SE secretion ST standards
SD supply & distribution TU therapeutic use
TO toxicity UL ultrastructure
UR urine  
Record Number:   52759 
Unique Identifier:   D054369 

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